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Radiation Oncology
Stritch School of Medicine

Sree Bash Chandra Debnath, PhD

Assistant Professor

Cancer is a leading cause of death globally, and ionizing radiation is widely used for its detection, monitoring, and treatment. More than two-thirds of cancer patients receive radiation therapy (RT) during their course of treatment. In recent years, advanced techniques such as small-field radiation therapy, ultra-high-dose rate therapy (e.g., FLASH) have been developed to deliver precise, accurate, and highly controlled doses to cancerous cells while sparing surrounding healthy tissues and organs at risk. However, this introduces significant challenges for dose characterization and estimation, as conventional dosimetry techniques are often inefficient. In this context, we are working on developing technologies for addressing key challenges in areas such as small-field radiation therapy, micro-dosimetry, scintillating dosimetry, ultra-high dose-rate dosimetry for protons and/or electrons, accuracy in radiation measurement, AI-integrated high-resolution imaging systems, and the development of detectors sensitive to ultra-high dose rates.

This research aims to achieve a paradigm shift in modern radiation therapy, ensuring quality treatment, improving the understanding of the effects of ionizing radiation on tissues, and pioneering high-resolution medical imaging technologies, thereby contributing to the advancement of early-stage cancer treatment.

Patents

  • Debnath, S.B.C.*, Fauquet, C., Tallet, A., Gonçalves, A., Darréon, J. and Tonneau, D., [Patent #FR1909611- WO2021043773A1, 09/2019] : SCINTILLATING X-RAY DOSIMETERS.
  • Debnath, S.B.C., Fauquet, C., Tallet, A., Gonçalves, A., Darréon, J. and Tonneau, D.*, [Patent # FR2100745 -ICG020685FR/PCT/EP2022/051424, 01/2021]: A DETECTOR OF THE FLUXES OF A FIRST AND A SECOND IONIZING RADIATION. US patent: “DOSIMETER”, US2022/0291397 Al, PCT/EP2020/074364; pub. Date -Sept 15,2022.

Education

B.Sc in Electrical and Electronic Engineering, Chittagong University of Engineering and Technology, Bangladesh

M.Sc in Telecommunications Engineering, University of Trento, Italy 

PhD  in  Medical Physics and Materials Science, Aix Marseille University - CNRS, France

Postdoctoral MSCA Global Fellowship at Argonne National lab, USA & PSI, Switzerland

Research Interests

  • Medical Physics, Radiation Dosimetry, Ionizing Radiation, Radiation Physics
  • Small-field Dosimetry, Proton Beam dosimetry, FLASH
  • Scintillating Dosimetry, Device Modelling, Instrumentation
  • X-ray imaging, Medical Imaging, AI-integrated Imaging

Professional/Community Affiliations

  • American Association of Physicists in Medicine (AAPM)
  • American Society for Therapeutic Radiology and Oncology (ASTRO)
  • European Society for Therapeutic Radiation and Oncology (ESTRO)
  • IEEE

Publications/Research Listings

  • Debnath, S. B. C.*, Tonneau, D., Fauquet, C., Tallet, A. and Darreon, J., 2024. Cerenkov free micro-dosimetry in small-field radiation therapy technique. Physics in Medicine and Biology.. https://doi.org/10.1088/1361-6560/ad51c6.
  • Lalanne, Debnath, S. B. C.* K.,Simonin, G., Tonneau, D., Vianna-Legros, F., Rousseau, M., Brasse, D., Darréon, J. and Fauquet, C., Geometrical Characterization of an Inorganic Scintillator Detector for Proton Therapy using a Micrometer Scale Ion Beam. IEEE Sensors Journal.Doi.org/10.1109/JSEN.2024.3401630.[Debnath is co-first author and corresponding author]
  • Debnath, S.B.C.*, Fauquet, C., Tallet, A., Goncalves, A., Lavandier, S., Jandard, F., Tonneau, D. and Darreon, J., 2020. High spatial resolution inorganic scintillator detector for high‐energy X‐ray beam at small field irradiation. Medical Physics, 47(3), pp.1364-1371.org/10.1002/mp.14002
  • Debnath, S.B.C.*, Tonneau, D., Fauque, C., Tallet, A., Goncalves, A. and Darreon, J., 2021. Dosimetric characterization of a small-scale (Zn, Cd) S: Ag inorganic scintillating detector to be used in radiotherapy. Physica Medica, 84, pp.15-23. https://doi.org/10.1016/j.ejmp.2021.03.022.
  • Simonin, G.*, Debnath, S.B.C., et al.,“Characterization of a high lateral resolution and high sensitivity dosimeter for proton beams using inorganic scintillator detector”. IEEE Sensors Journal. DOI:10.1109/JSEN.2024.3502906.
  • Debnath, S.B.C.*, Ferre, M., Tonneau, D., Fauquet, C., Tallet, A., Goncalves, A. and Darreon, J., 2021. High resolution small‐scale inorganic scintillator detector: HDR brachytherapy application. Medical Physics, 48(4), pp.1485-1496.org/10.1002/mp.14727
  • Debnath, S.B.C.*, Darréon, J., Tallet, A., Gonçalves, A., Tonneau, D. and Fauquet, C., 2021. Signal amplification of fiber integrated X-ray detector and energy independence. IEEE Sensors Journal, 21(17), pp.18793-18799.org/10.1109/JSEN.2021.3091660.
  • Debnath, S. B. C.* 2017, July. TTW life sign detection by means of CW X-band radar, homeland security and rescue applications. In 2017 USNC-URSI Radio Science Meeting (Joint with AP-S Symposium)(pp. 89-90). IEEE. . DOI: 10.1109/USNC-URSI.2017.8074911.
  • Debnath, S. B. C.*,Tonneau, D., Fauquet, C., Tallet, A.R., Goncalves, A., Ferre, M. and Darreon, J., 2020. Small Scale Inorganic X-ray Detector for Dosimetry in Radiotherapy and Brachytherapy. International Journal of Radiation Oncology, Biology, Physics, 108(3), p.e251. https://doi.org/10.1016/j.ijrobp.2020.07.605.
  • Darréon, J*., Debnath, S. B. C, Benkreira, M., Fau, P., Mailleux, H., Ferré, M., Benkemouche, A., Tallet, A., Annede, P., Petit, C. and Salem, N., 2024. A novel lung SBRT treatment planning: Inverse VMAT plan with leaf motion limitation to ensure the irradiation reproducibility of a moving target. Medical Dosimetry, 49(2), pp.159-164. DOI: 10.1016/j.meddos.2023.11.001
  • Debnath, S. B. C.*, Shill, P.C. and Murase, K., 2013. Particle swarm optimization based adaptive strategy for tuning of fuzzy logic controller. International Journal of Artificial Intelligence & Applications, 4(1), p.37. DOI: 10.5121/IJAIA.2013.4104.
  • Debnath, S. B. C. *, Tonneau, D., Fauquet, C., Tallet, A.R., Ferre, M. and Darreon, J., 2022. A Novel Micro-Dosimetry Technique to Advance Small-Field Radiation Therapy Treatment. International Journal of Radiation Oncology, Biology, Physics, 114(3), p.S87.. org/10.1016/j.ijrobp.2022.07.496. 
  • Debnath, S. B. C.* (2020). New generation X-ray detector for radiation therapy and instrumentation for surface physics (Doctoral dissertation, Aix-Marseille). 
  • Lohan, E. S., Kauppinen, T., & Debnath, S. B. C. (2016, November). A survey of people movement analytics studies in the context of smart cities. In Open Innovations Association (FRUCT), 2016 19th Conference of (pp. 151-158). IEEE. DOI: 10.23919/FRUCT.2016.7892195.
  • Debnath, S. B. C. *, Barua, B., Karim, R., & Faisal, M. U. (2016, September). Design & implementation of an efficient windmill anemometer for wind speed measurement using microcontroller. In Electrical Engineering and Information Communication Technology (ICEEICT), 2016 3rd International Conference on (pp. 1-5). IEEE. DOI: 10.1109/CEEICT.2016.7873109
  • Debnath, S. B. C., Barua, B*., Islam, M. R., Alam, S., & Afroz, F. (2016, September). A feasibility study & simulative development of hybrid power plant using renewable energy at isolated island Kutubdia in Bangladesh. In Electrical Engineering and Information Communication Technology (ICEEICT), 2016 3rd International Conference on (pp. 1-5). IEEE. DOI: 10.1109/CEEICT.2016.7873122